SARMS have managed to do what anabolic steroids couldn’t in the past seven decades.
Its captured the imagination of the common public.
Everyone from the average fitness buff to athletes, to even bodybuilders are now switching over to SARMS in place of gear.
In fact, we haven’t witnessed such a widespread interest in PEDs since the time of designer steroids and prohormones.
And we can totally relate to it.
For the first time, a lifetime natural athlete or fitness buff can consider using a performance enhancement drug without worrying about losing their hair or battering their endocrine system beyond repair.
No bitch tits. No infertility.
But, it’s still early days for these amazing drugs. Not even one of them is approved for human consumption yet.
So there’s a lot of misinformation and broscience being doled out there by condescending self-proclaimed gurus who claim to have run multiple cycles of almost every SARM in circulation.
If you are new to SARMS and are looking for unbiased information on these compounds, then this guide will help you understand what to expect from SARMS and how to use them safely.
Strap in and enjoy the read.
What are SARMS?
SARMS are non-steroidal, androgen receptor ligands that attach to specific androgen receptors in the body and stimulate them to produce a desired reaction.
For example, some SARMS may bind to AR in the muscle and bone tissue while sparing the receptors in the prostate gland.
This could be very favorable in a variety of therapeutic applications which currently rely on anabolic androgenic agents. The usage though is severely limited because of the androgenic side effects of these compounds.
The first attempt to develop SARMS dates back to the 1940s when researchers attempted to create an anabolic compound that would not have the unfavorable side effects of testosterone.
However, it would be years before the first SARM would see the light of the day.
In the early 1990s, several major pharmaceutical corporations began funding research for the development of SARMS for the treatment of sarcopenia, cachexia due to terminal illness and for the treatment of BPH.
Numerous pre-clinical trials were conducted to generally positive outcomes.
At least two of these compounds have made it to Phase II of human clinical trials.
How do SARMS work?
In a nutshell, these drugs work exactly like SERMS do.
SERMS are selective estrogen receptor modulators like Nolvadex and Clomid.
These drugs work by binding to estrogen receptors in specific areas like the mammary tissue, which in turn prevents estrogen molecules from binding to it. This prevents the spread of receptor-positive breast cancer cells in the body.
In other organs, like the liver, the SERM may actually work as an Estrogen receptor agonist, which in turn helps reduce the levels of LDL cholesterol.
Similarly, SARMS work by binding themselves to androgen receptors and signaling them to produce more muscle, increase strength and reduce body fat, which are the anabolic effects.
However, these compounds display excellent tissue specificity and completely or partially spare the androgen receptors in the prostate gland. This prevents the prostate related complications that anabolic steroids can cause.
Also, since SARMS do not aromatize, there is no risk of it causing gynecomastia or virilization in females.
At least that’s what we know currently.
What are the SARMS that are being sold currently in UG labs?
SARMS sold online are labelled as research chemicals that are not for human consumption.
While there are many SARMS that are being used illegally in the bodybuilding community, these are the most commonly used one.
Known as the Testosterone alternative of the SARMS world. Used primarily for bulking cycles. Users have been able to gain 10-15 lbs. of mass in just 8-weeks of LGD cycles which is incredible for a SARM. Along with the increased mass, most users also report dramatic strength gains, reduced body fat and vascularity.
While the comparison may not entirely be correct, this could well be the Trenbolone alternative. Lean, clean gains, great pumps, vascularity and fat loss. Rad-140 is used primarily for body recomposition cycles. Many users stack it with other compounds to amplify their results.
A weaker version of LGD-4033 that is used mainly for preserving muscle during cuts. However, it can also be used for a clean bulk, especially if it’s stacked with other compounds like GW501516. Most first time SARMS users hop on to an Ostarine cycle since it is less likely to cause as many side effects as LGD or RAD can.
While this is not a SARM, it is often sold alongside and stacked together with SARMS. Cardarine is a cutting compound that increases fatty acid oxidation and trims body fat especially from the waist. It increases your endurance and allows you to go for much longer with cardio and your lifts.
Often touted to be the Winstrol alternative of the SARM world, S4 was one of the first SARMS to hit UG labs. It boosts energy, burns fat, preserves and even increases lean muscle and hardens you up. The pumps and vascularity lasts for weeks after the cycle. However, there are some concerns with vision related sides which have limited its use.
The newest kid on the block, YK-11 is believed to be more anabolic than DHT itself. How’s that for a reputation. The results include dramatic increase in strength, size and fat burn. However, most anecdotal reviews suggest extreme suppression of your endogenous testosterone. So running it without a test base might not be a smart decision.
Again, this isn’t a SARM. But it’s often labelled and sold together with other SARMS It is a Ghrelin mimetic and GH secretagogue that increases the GH pulses that our bodies produce. It is used as an off-season compound for maintaining the gains that are achieved with a SARMS cycle. It helps in increasing fat free mass and is very effective in bulking cycles because of the increased appetite that it stimulates.
What results can be achieved with SARMS?
Like we mentioned earlier, we are still in the nascent stage of SARMS usage.
Dosage and cycle duration are based on caution to derive the best results while minimizing side effects.
So, steroid-like results are still a pipe dream with these drugs.
In fact, if you have done real gear, then you might find it too mild for your liking.
That’s why we frequently come across threads on messaging boards that say that SARMS are a waste of time and money.
But, if you have been a lifelong natural athlete, then with time and effort, there is no reason why you cannot achieve your body goals with SARMS.
You can bulk, cut, recomp.
There are users who have run multiple cycles of LGD-4033 and retained most of their gains. Ditto with RAD.
You just need to know what you are doing and be persistent.
Do not go into your SARMS cycle with exaggerated expectations. It’s not a Tren Ace cycle for god’s sake.
SARMS vs. Oral steroids
This comparison is inevitable, isn’t it?
Both compounds don’t require you to pin. Both can produce some great results.
You might just wonder whether it’s better to do oral steroid only cycles as opposed to SARMS.
But there are some caveats to that.
Better results than SARMS but risk of severe side effects
Suppression in men
No virilization in females
Complete shutdown of endogenous testosterone
So, unless you are thinking of running very mild oral steroids like low dose Anavar, SARMS are always the better bet.
In the early days of SARMS, pseudo gurus were busy trashing users who considered stacking SARMS, citing some half-baked facts about how these compounds might compete for the same androgen receptor.
But, it has been proven repeatedly that SARMS produce great results when stacked. Many of these compounds work perfectly in synergy and might be instrumental in helping you achieve your bodybuilding goals.
There are men who stack Test, Deca, Tren and Mast, but make a beeline for the hills when you talk to them about stacking LGD and RAD.
Don’t get swayed by this bull crap. Go ahead and stack SARMS provided you have the experience with it.
If it’s your first SARMS cycle, keep it simple. Run one compound and understand how your body reacts to it.
How to use SARMS
Use it responsibly. That’s the best advice that we can give you.
- Don’t go crazy with the doses.
- Don’t run it forever. Stick to 8-week cycles. (Except for MK-677)
- Take 2x the time off if you can. Else time on=time off. After you run an 8-week cycle, take at least 8-weeks off. 16-weeks is better. Allow your body enough time to recover.
- Add on-cycle support.
- Do bloodwork prior, during and after your cycle.
- Check your hormone levels and your lipids because these are most likely to get affected.
- Watch out for sides. If you feel that something is way off, then it probably is. Stop or back off.
- Be aware of the sides for the compound that you are planning to use. Be prepared for undocumented sides as well.
- Buy from a reputed supplier or source. You don’t want to end up buying anything that is under dosed or laced with prohormones.
Here are some recommended doses for first timers.
7.5mg – 12.5mg/day. Some users increase this to 20mg/day during the last couple of weeks. That’s fine as long as you are not experiencing too many side effects.
5mg/day to 10mg/day. This dose usually suffices to produce great results. There are users who might dose even 30mg/day. These are the ones who run 1200mg of test per week. Don’t be that guy.
7.5mg/day to 10mg/day. Some users increase to 15 and even 20mg/day. Watch out for the suppression. It can hit you real bad.
Start off with 25mg/day and bump it to 50mg/day in the second and third week. Only if you don’t get the vision sides at 50, you can bump it up to 75mg/day. If you still don’t get the vision sides, you are gifted. Go for 100mg/day. This can produce some crazy results.
10mg/day for two weeks followed by 20mg/week for the remainder of the cycle. That’s the highest that we’d go with Cardarine.
20mg/day works fine for most people. MK-677 can be run for 16-weeks or even more without too many problems. Just that you will be hungry as hell most of the time. At least until the hunger subsides.
Do you need a PCT with SARMS?
That depends on how hard the suppression hits you. There’s only one way to know for sure, bloodwork.
Don’t skimp on the bloodwork. Remember that many a time, suppression can occur even without causing too many obvious symptoms.
If you are suppressed more than 70% and if your LH and FSH levels have crashed, a mini PCT should help you bounce back a lot sooner.
On the other hand, if the suppression is mild, then you can do without a PCT. Just use some D-Aspartic acid, zinc and M1-MK to restore your testosterone levels back.
Can you use SARMS with SERMS?
A lot of users have started to add SERMS like Nolva, Clomid or Torem to their cycles to keep their endogenous test levels from crashing.
This is definitely effective and will keep your wiener working and your libido up. However, it’s still uncharted turf.
Besides, the dosage for SERMS needs to be dialed down. If you go too high, you open up a whole new level of side effects.
Also, not everybody feels the same on SERMS. Some find that their mood is enhanced greatly. While others get as emotional as a child who’s lost their candy.
So it’s a line that we’d tread carefully.
Using SARMS with steroids
Now we are talking.
SARMS can definitely be stacked with anabolic steroids.
- There’s no risk of suppression.
- Many SARMS can amplify the results that you’d get from a steroid cycle.
- Some of these compounds are used for reducing dyslipidemia.
If you are on TRT, hop on to an LGD-4033 cycle or even RAD-140 to lean out and get great gains.
We recently saw a thread where someone ran RAD-140 with Oxandrolone for 8-weeks and looked absolutely peeled.
Produce Lean Muscle
Reduce Body Fat
Do Not Aromatize